Full Schedule

5:30 AM – 6:15 AM MST

Phoenix Running Tour

Location: 3rd and Monroe street

7:00 AM – 7:30 AM MST

30 Minute Guided Meditation

Location: 230 North

7:00 AM – 8:30 AM MST

Breakfast

7:00 AM – 9:00 AM MST

JCF Editorial Board Meeting

Location: Sheraton Hotel- Camelback

Affiliate Meeting

7:00 AM – 5:00 PM MST

Meditation/Quiet Room

Location: 230 North

7:15 AM – 9:15 AM MST

PGR--Physicians Grand Rounds

Location: 101 A-C (West)

Chair: – Northwestern University

Chair: – University of Pennsylvania

CLIN

7:15 AM – 9:15 AM MST

PGR1- Profound electrolyte and acid-base disturbances in an infant with CF

Location: 101 A-C (West)

Speaker: – Pediatric Pulmonology ,UVM Children's Hospital, Burlington, VT, USA

7:15 AM – 9:15 AM MST

PGR2- Complications of Standard Acute Systolic Heart Failure Therapy in a Person with CF

Location: 101 A-C (West)

Speaker: – Emory University

7:15 AM – 9:15 AM MST

PGR3- Cannabis use in a young adult with CF

Location: 101 A-C (West)

Speaker: – Cincinnati Children’s Hospital/University of Cincinnati College of Medicine

7:15 AM – 9:15 AM MST

PGR4- R117H variant presenting as chronic sinusitis in an adult with CF

Location: 101 A-C (West)

Speaker: – UAB

7:15 AM – 9:15 AM MST

PGR1 Discussion- Profound electrolyte and acid-base disturbances in an infant with CF

Location: 101 A-C (West)

Discussant: – University of Wisconsin

7:15 AM – 9:15 AM MST

PGR2 Discussion- Complications of Standard Acute Systolic Heart Failure Therapy in a Person with CF

Location: 101 A-C (West)

Discussant: – All Wales Adult CF Centre, Cardiff and Vale University Health Board, Cardiff, UK

7:15 AM – 9:15 AM MST

PGR3 Discussion- Cannabis use in a young adult with CF

Location: 101 A-C (West)

Discussant: – University of Pittsburgh

7:15 AM – 9:15 AM MST

PGR4 Discussion- R117H variant presenting as chronic sinusitis in an adult with CF

Location: 101 A-C (West)

Discussant: – Johns Hopkins University

7:15 AM – 9:15 AM MST

W01--Infection/Inflammation Models in CF

Location: 103 AB (West)

Chair: – University of Alabama at Birmingham

Chair: – Infection and Cystic Fibrosis Unit, IRCCS San Raffaele Scientific Institute, Milan, Italy

IMIAPPTT

7:15 AM – 9:15 AM MST

W01.1- Cystic Fibrosis Airway Inflammation Enhances the Efficacy of CFTR Modulators

Location: 103 AB (West)

Speaker: – The University of North Carolina at Chapel Hill

7:15 AM – 9:15 AM MST

W01.2- Systems Serology in Cystic Fibrosis: Anti-Pseudomonas IgG1 Responses and Reduced Lung Function

Location: 103 AB (West)

Speaker: – Tulane University

7:15 AM – 9:15 AM MST

W01.3- Ezrin is required to maintain the number and function of tissue resident alveolar macrophages (TRAMs) in CF during infection.

Location: 103 AB (West)

Speaker: – Yale University School of Medicine

7:15 AM – 9:15 AM MST

W01.4- Unraveling the dark side of CF inflammation: Cellular senescence

Location: 103 AB (West)

Speaker: – Azienda Ospedaliera Universitaria Integrata di Verona

7:15 AM – 9:15 AM MST

W01.5- Unveiling the role of gutas a player in lung inflammation using novel Collaborative Cross mice with ΔF508-Cftrmutation

Location: 103 AB (West)

Speaker: – Infection and Cystic Fibrosis Unit, IRCCS San Raffaele Scientific Institute, Milan, Italy

7:15 AM – 9:15 AM MST

W02--Model Systems to Study Non-Pulmonary Manifestations of CF

Location: 207 Lecture Hall (West)

Chair: – Vanderbilt University Medical Center

Chair: – Cincinnati Children's Hospital

EPP

7:15 AM – 9:15 AM MST

W02.1- Role of Diet in Pregnancy Associated Morbidity in Cystic Fibrosis Ferrets

Location: 207 Lecture Hall (West)

Speaker: – National Ferret Research and Resource Center

7:15 AM – 9:15 AM MST

W02.2- Gut microbiota contributions to intestinal disease in CF

Location: 207 Lecture Hall (West)

Speaker: – Cleveland Clinic

7:15 AM – 9:15 AM MST

W02.3- Establishment of primary sweat gland cultures suitable for CFTR functional and RNA analysis

Location: 207 Lecture Hall (West)

Speaker: – Johns Hopkins School of Medicine

7:15 AM – 9:15 AM MST

W02.4- Single-cell multi-omics profiling reveals novel regulatory networks of CFTR in the kidney

Location: 207 Lecture Hall (West)

Speaker: – University of Virginia

7:15 AM – 9:15 AM MST

W02.5- Myokine production in CF mouse skeletal muscle differs from wild type controls

Location: 207 Lecture Hall (West)

Speaker: – Case Western Reserve University

7:15 AM – 9:15 AM MST

W03--Pulmonary Vascular Biology & Lung Transplantation

Location: 105 C (West)

Chair: – University of Toronto, Hospital for Sick Children

Chair: – Washington University in St. Louis

APPTT

7:15 AM – 9:15 AM MST

W03.1- Lung Transplant Recipients with CF: Perspectives on the Use of Elexacaftor/Tezacaftor/Ivacaftor

Location: 105 C (West)

Speaker: – University of Washington

7:15 AM – 9:15 AM MST

W03.2- Psoas Muscle Area May be a Useful Measure to Predict Fracture Risk in Persons with CF Undergoing Lung Transplant.

Location: 105 C (West)

Speaker:

7:15 AM – 9:15 AM MST

W03.3- Pulmonary Vascular Remodeling in Cystic Fibrosis Begins early in the Disease and at Young Age

Location: 105 C (West)

Speaker: – Cincinnati Children's Hospital Medical Center

7:15 AM – 9:15 AM MST

W03.4- Non-tuberculous Mycobacterial Infection as a Barrier to Lung Transplantation in Patients with Cystic Fibrosis

Location: 105 C (West)

Speaker: – Medical University of South Carolina

7:15 AM – 9:15 AM MST

W03.5- Preparing people with CF for lung transplant discussions and decisions: Qualitative outcomes in a pilot randomized control trial of a CF-specific educational website

Location: 105 C (West)

Speaker: – University of Washington

7:15 AM – 9:15 AM MST

DG04--APP Grand Rounds

Location: 124 AB (North)

Chair: – Indiana University Adult CF Center

Chair: – WVU Medicine Childrens Hospital

Speaker: – Oregon Health & Science University

Speaker: – Oklahoma Children's Hospital

Speaker: – Thomas Jefferson University Health

Speaker: – Texas Tech Health Science Center

NRS

7:15 AM – 9:15 AM MST

DG05--Who You Gonna Call ? Ethical Decision Making in CF

Location: 224 AB (North)

Chair: – SUNY Upstate Medical University

Chair: – Northwestern University

Speaker: – UNC-CH

Speaker: – Ann & Robert H. Lurie Children's Hospital of Chicago

Speaker: – Upstate University Hospital

Speaker: – Ventura County Medical Center

Speaker: – University of Utah Hospital

SW/PSYCH

7:15 AM – 9:15 AM MST

DG06--Jeopardy!

Location: 127 A-C (North)

Chair: – University of Rochester

Chair: – The Children's Hospital of Philadelphia

Speaker: – University of Rochester

Speaker: – The Children's Hospital of Philadelphia

PT/RT

7:15 AM – 9:15 AM MST

DG07--Aging Well With CF: A Nutrition Perspective

Location: 129 AB (North)

Chair: – New York Presbyterian/Columbia University Irving Medical Center

Chair: – Indiana University Health

Speaker: – University of Utah Adult CF Team

Speaker: – St. Michael's Hospital

Community Speaker: – Restorative Connection Counseling

NTR

7:15 AM – 9:15 AM MST

DG08--Cannonball!!!: Topics Making a Big Splash in CF Ambulatory Care

Location: 121 A-C (North)

Chair: – IU Health

Chair: – SSM Health Cardinal Glennon Children's Hospital

Speaker: – Northwestern Medicine

Speaker: – Primary Children's Hospital

Speaker: – CVS Specialty Pharmacy

Speaker: – University of Iowa Hospitals and Clinics

Speaker: – University of Utah

PHARM

7:15 AM – 9:15 AM MST

DG09--Genetics for Research Coordinators

Location: 122 A-C (North)

Chair: – University of Alabama at Birmingham

Speaker: – University of Alabama at Birmingham

Speaker: – University of California Irvine; Long Beach Memorial and Miller Children’s and Women’s Hospital

Speaker: – National Jewish Health

CLIN

7:15 AM – 9:15 AM MST

DG10--Education: From Binders & Checklists to YouTube and TikTok

Location: 229 AB (North)

Chair: – Geisinger Medical Center

Chair: – Levine Children's

Speaker: – American Family Children's Hospital

Community Speaker: – Tiktok

Community Speaker: – University of Michigan

Speaker: – University of Michigan Health

Speaker: – Ann & Robert H. Children's Hospital of Chicago

Speaker: – Lurie Children's Hospital of Chicago

NRS

7:15 AM – 9:15 AM MST

DG11--Genetics & Genetic Counseling for CF

Location: 226 A-C (North)

Chair: – Case Western Reserve University

Chair: – Lenox Hill Hospital/Northwell Health

Speaker: – University of California, San Francisco

Speaker: – Cincinnati Children's Hospital

Speaker: – Icahn School of Medicine at Mount Sinai

CLIN

8:00 AM – 5:00 PM MST

Patient Registry Classroom

Location: Convention Center-223 (North)

Affiliate Meeting

8:00 AM – 7:30 PM MST

Exhibit & Poster Hall Hours

Location: Exhibit & Poster Hall 300 level (West)

8:30 AM – 9:10 AM MST

RFPT02--Real World Impact of CFTR Modulators

Location: Theater B (Exhibit & Poster Hall)

Chair: – Northwestern University Feinberg School of Medicine

Chair: – University of Washington School of Medicine

CLIN

8:30 AM – 9:10 AM MST

RFPT02.1- Effects of elexacaftor/tezacaftor/ivacaftor (ETI) modulator usage during cystic fibrosis pregnancies on maternal and neonatal outcomes

Location: Theater B (Exhibit & Poster Hall)

Speaker: – Clinical Nutrition, Nebraska Medicine, Omaha, NE, USA

8:30 AM – 9:10 AM MST

RFPT02.2- Outcomes of Cessation of CFTR Modulator Therapy: An Unfortunate Experience

Location: Theater B (Exhibit & Poster Hall)

Speaker: – Marmara University Medical Faculty

8:30 AM – 9:10 AM MST

RFPT02.3- Neurologic and mental health adverse events with CFTR modulator therapies at a single CF center

Location: Theater B (Exhibit & Poster Hall)

Speaker: – University Hospitals Rainbow Babies & Children's Hospital

8:30 AM – 9:10 AM MST

RFPT02.4- CFTR modulator use is associated with reduced risk of incident NTM infection

Location: Theater B (Exhibit & Poster Hall)

Speaker: – University of Michigan Health

8:30 AM – 9:10 AM MST

RFPT02.5- Patient Perspectives on Clinic Visits in the Era of Highly Effective Modulator Therapy

Location: Theater B (Exhibit & Poster Hall)

Speaker: – Dell Medical School

8:30 AM – 9:10 AM MST

RFPT02.6- Provider Practices in the Management of Pulmonary Exacerbation in the Era of Highly Effective Modulator Therapy

Location: Theater B (Exhibit & Poster Hall)

Speaker: – Johns Hopkins University

8:30 AM – 9:10 AM MST

RFPT02.7- Lipid concentrations following 12-18 months of clinically-prescribed elexacaftor/tezacaftor/ivacaftor—PROMISE sub-study

Location: Theater B (Exhibit & Poster Hall)

Speaker: – Children's Hospital of Philadelphia

8:30 AM – 9:10 AM MST

RFPT02.8- Effects of elexacaftor/tezacaftor/ivacaftor on antibiotic use in people with cystic fibrosis

Location: Theater B (Exhibit & Poster Hall)

Speaker: – UNC Health

8:30 AM – 9:10 AM MST

RFPT01--Technologies to Achieve Efficient & Durable CFTR Rescue

Location: Theater A (Exhibit & Poster Hall)

Chair: – Stead Family Department of Pediatrics

Chair: – University of North Carolina

PTAC/CFTR

8:30 AM – 9:10 AM MST

RFPT01.1- Modulator response of rare CFTR missense variants not approved for elexacaftor/tezacaftor/ivacaftor (ETI)

Location: Theater A (Exhibit & Poster Hall)

Speaker: – Emory University / School of Medicine / Department of Pediatrics

8:30 AM – 9:10 AM MST

RFPT01.2- Organoid-guided Synergistic Treatment of Minimal Function CFTR Mutations with CFTR modulators, Roflumilast and Simvastatin: A Personalized Approach

Location: Theater A (Exhibit & Poster Hall)

Speaker: – UMCU

8:30 AM – 9:10 AM MST

RFPT01.3- First in Human clinical trial with SPL84, an ASO for treatment of CF patients carrying the 3849 +10 Kb C - > T mutation

Location: Theater A (Exhibit & Poster Hall)

Speaker: – SpliSense, Hadassah University Hospital

Speaker: – SpliSense Ltd., Jerusalem, Israel

8:30 AM – 9:10 AM MST

RFPT01.4- Beyond SION-638: a novel series of highly potent stabilizers of NBD1 enable full correction of ΔF508-CFTR in a dual combination with Sionna CFTR modulators, providing a path to wild-type function.

Location: Theater A (Exhibit & Poster Hall)

Speaker: – Sionna Therapeutics

8:30 AM – 9:10 AM MST

RFPT01.5 - Rescuing G542X by Adenine Base Editing: A guide to restore function

Location: Theater A (Exhibit & Poster Hall)

Speaker: – University College Cork

8:30 AM – 9:10 AM MST

RFPT01.6- A W1282X mouse model for cystic fibrosis and in vitro correction of the phenotype by pharmacologics and gene editing

Location: Theater A (Exhibit & Poster Hall)

Speaker: – Case Western Reserve University

8:30 AM – 9:10 AM MST

RFPT01.7- CFTR function is restored in CF rats treated with airway gene-addition therapy as neonates

Location: Theater A (Exhibit & Poster Hall)

Speaker: – University of Adelaide

8:30 AM – 9:10 AM MST

RFPT01.8- Durable fCFTR∆R transgene expression and efficient re-administration after rAAV2.5T-mediated gene transfer to adult ferret lungs

Location: Theater A (Exhibit & Poster Hall)

Speaker: – Anatomy and Cell Biology, University of Iowa, Iowa City, IA, US

8:30 AM – 10:30 AM MST

AM Coffee Break

9:15 AM – 9:45 AM MST

30 Minute Guided Meditation

Location: 230 North

9:30 AM – 11:00 AM MST

TPS01--Stem Cell Biology, Reprogramming, and Engraftment in CF Lungs

Location: Theater C (Exhibit & Poster Hall)

Chair: – University of Iowa

Chair: – Boston University Medical Center

PTAC/CFTR

9:30 AM – 11:00 AM MST

TPS01.1- iPSC-derived airway basal cells that exhibit increased competence for multipotent differentiation

Location: Theater C (Exhibit & Poster Hall)

Speaker: – UTHealth

9:30 AM – 11:00 AM MST

TPS01.2- An open-label trial to evaluate ETI and iPSC-derived model systems among individuals with residual CFTR activity

Location: Theater C (Exhibit & Poster Hall)

Speaker: – Emory University and Children's Healthcare of Atlanta

9:30 AM – 11:00 AM MST

TPS01.3- Generation of airway basal stem cells from iPSC-derived airway progenitors: elucidation of signaling pathways responsible for basal cell maturation and proliferation

Location: Theater C (Exhibit & Poster Hall)

Speaker: – University of Alabama at Birmingham

9:30 AM – 11:00 AM MST

TPS01.4- Standardization and Utilization of Human Induced Pluripotent Stem Cells for In Vitro Disease Modelling of Cystic Fibrosis

Location: Theater C (Exhibit & Poster Hall)

Speaker: – Cystic Fibrosis Foundation

9:30 AM – 11:00 AM MST

TPS01.5- Targeted disruption of FOXI1 results in pulmonary ionocyte deficient airway epithelium in an iPSC-airway system

Location: Theater C (Exhibit & Poster Hall)

Speaker: – Boston Children's Hospital

9:30 AM – 11:00 AM MST

TPS01.6- A Common FOXI1-Lineage Progenitor Specifies Pulmonary Ionocyte, PNECs, and Tuft cells

Location: Theater C (Exhibit & Poster Hall)

Speaker: – University of Iowa

9:30 AM – 11:00 AM MST

TPS01.7- Generation of Fully Differentiated and Functional Human Small Airway Cultures

Location: Theater C (Exhibit & Poster Hall)

Speaker: – STEMCELL Technologies Inc.

9:30 AM – 11:00 AM MST

TPS01.8- Role of CFTR in airway epithelial regeneration and repair: Studies from novel human basal cell lines

Location: Theater C (Exhibit & Poster Hall)

Speaker: – BioISI – Biosystems & Integrative Sciences Institute, Faculty of Sciences, University of Lisboa, Lisboa Portugal

9:30 AM – 11:00 AM MST

TPS01.9- Patient-derived 3D lung airway model to study mucociliary clearance

Location: Theater C (Exhibit & Poster Hall)

Speaker: – Cedars Sinai Medical Center

9:30 AM – 11:00 AM MST

TPS01.10- A lipid nanoparticle arsenal to correct cystic fibrosis in airway stem cells.

Location: Theater C (Exhibit & Poster Hall)

Speaker: – UCLA

9:45 AM – 11:45 AM MST

W04--Best Practice & Innovative Approaches to Clinical Research

Location: 207 Lecture Hall (West)

Chair: – Medical College of Wisconsin

Chair: – National Jewish Health

CLIN

9:45 AM – 11:45 AM MST

W04.1- Improving accuracy of patient summary reports from CFSmartReports: A QI project

Location: 207 Lecture Hall (West)

Speaker: – University of Oklahoma Health Sciences Center

9:45 AM – 11:45 AM MST

W04.2- Building Trust in CF Research: Use of hands-on conversations to gauge trust in researchers performing phase I clinical trials.

Location: 207 Lecture Hall (West)

Speaker: – University of Iowa Hospitals and Clinics

9:45 AM – 11:45 AM MST

W04.3- Home reported outcomes (HERO-2) in people with CF taking elexacaftor/tezacaftor/ivacaftor: Feasibility for Conducting a Real-World protocol

Location: 207 Lecture Hall (West)

Speaker: – Riley Hospital for Children/Indiana University

9:45 AM – 11:45 AM MST

W04.4- Research Coordination Perceptions of a Coached Home Spirometry Protocol: Ongoing Experiences with the OUTREACH Study

Location: 207 Lecture Hall (West)

Speaker: – Boston Children's Hospital

9:45 AM – 11:45 AM MST

W04.5- Fostering provider engagement through effective meeting strategies.

Location: 207 Lecture Hall (West)

Speaker: – National Jewish Health

9:45 AM – 11:45 AM MST

W05--Rescuing CFTR Premature Truncation Alleles: Basic Biology & Novel Therapeutic Strategies

Location: 105 C (West)

Chair: – University of Rochester School of Medicine and Dentistry

Chair: – Cystic Fibrosis Research Center, University of Alabama at Birmingham.

PTAC/CFTR

9:45 AM – 11:45 AM MST

W05.1- Development Of An Improved Adenine Base Editor To Correct W1282X-CFTR With Reduced Bystander Effects

Location: 105 C (West)

Speaker: – BioISI – BioSystems and Integrative Sciences Institute, Faculty of Sciences, University of Lisbon

9:45 AM – 11:45 AM MST

W05.2- LUNAR®-CFTR mRNA replacement therapy restores CFTR expression and function in human bronchial epithelial cells

Location: 105 C (West)

Speaker: – University of Alabama at Birmingham

9:45 AM – 11:45 AM MST

W05.3- Functional and RNA-level recovery of CFTR nonsense variants with NMD inhibition, readthrough, and ETI

Location: 105 C (West)

Speaker: – Johns Hopkins School of Medicine

9:45 AM – 11:45 AM MST

W05.4- One ACE-tRNA sequence can functionally rescue the most prevalent CFTR nonsense mutations

Location: 105 C (West)

Speaker: – University of Rochester Medical Center

9:45 AM – 11:45 AM MST

W05.5- SPL84, Antisense oligonucleotide modulating the 3849+10kb C-T splicing defect, efficiently penetrates and restores CFTR function when treated through the apical side of primary HBE cells

Location: 105 C (West)

Speaker: – splisense

9:45 AM – 11:45 AM MST

W06-- Best of Nutrition Research

Location: 103 AB (West)

Chair: – UT Health San Antonio

Chair: – Children's Healthcare of Atlanta

NTR

9:45 AM – 11:45 AM MST

W06.1- Food insecurity screening and local food access: Contributions to nutritional outcomes across CF programs in the United States

Location: 103 AB (West)

Speaker: – University of Alabama at Birmingham

9:45 AM – 11:45 AM MST

W06.2- Adiposity is associated with glucose intolerance in adults with CF in the CFTR modulator era

Location: 103 AB (West)

Speaker: – Emory University School of Medicine

9:45 AM – 11:45 AM MST

W06.3- Eating behaviors and appetite in children with CF aged 2-5 years: FIRST study

Location: 103 AB (West)

Speaker: – Primary Children's Hospital

9:45 AM – 11:45 AM MST

W06.4- Acid suppression therapy and associations with growth, gut microbiome, and early-onset lung disease in young children with cystic fibrosis

Location: 103 AB (West)

Speaker: – University Of Wisconsin School Of Medicine & Public Health

9:45 AM – 11:45 AM MST

W06.5- Dietary fat intake is associated with increased bone mineral density and lean mass in adults with cystic fibrosis

Location: 103 AB (West)

Speaker: – Emory University

9:45 AM – 11:45 AM MST

W07--National & International Models of Quality Improvement

Location: 104 AB (West)

Chair: – Monroe Carell Jr. Children's Hospital at Vanderbilt

Chair: – Children's of Alabama

CLIN

9:45 AM – 11:45 AM MST

W07.1- Transforming Transition: Take Two!

Location: 104 AB (West)

Speaker: – UVA Pediatric Cystic Fibrosis Program

9:45 AM – 11:45 AM MST

W07.2- Impact of Effective CF Center Team Training in a Low and Middle-Income Country.

Location: 104 AB (West)

Speaker: – Dr. J.P. Garrahan

9:45 AM – 11:45 AM MST

W07.3- A cystic fibrosis learning network innovation lab examining health related quality of life.

Location: 104 AB (West)

Speaker: – University of Minnesota

9:45 AM – 11:45 AM MST

W07.4- Creation of an Abnormal Newborn Screen Response Team improves timeliness of sweat chloride testing

Location: 104 AB (West)

Speaker: – Nationwide Children's Hospital

9:45 AM – 11:45 AM MST

W07.5- Improving accuracy of self-identification of race and ethnicity among people with cystic fibrosis at a pediatric care center

Location: 104 AB (West)

Speaker: – Seattle Children's Hospital

9:45 AM – 11:45 AM MST

W08--Lung Transplant Updates, What's New?!

Location: 231 A-C (North)

Chair: – NYP-Columbia Hospital

Chair: – UCLA Health

PT/RT

9:45 AM – 11:45 AM MST

W08.1- Advanced Lung Disease and Standardizing a Transplant Referral Protocol

Location: 231 A-C (North)

Speaker: – UTSW/Children's Health

9:45 AM – 11:45 AM MST

W08.2- An Early Lung Transplant Education Intervention with a Focus on Social-emotional Readiness

Location: 231 A-C (North)

Speaker: – University of Vermont Medical Center

9:45 AM – 11:45 AM MST

W08.3- A single adult CF center initiative to improve patient understanding of lung transplantation processes.

Location: 231 A-C (North)

Speaker: – Michigan Medicine, University of Michigan

Speaker: – Michigan Medicine

Community Speaker:

9:45 AM – 11:45 AM MST

W08.4- We Be-lung Together: EMST for Lung Transplant Recipients with Dysphagia

Location: 231 A-C (North)

Speaker: – New York Presbyterian-Columbia University Irving Medical Center

Speaker: – New York Presbyterian

9:45 AM – 11:45 AM MST

W08.5- Lung transplant journey from the patient perspective (Patient interviews)

Location: 231 A-C (North)

Speaker: – Morgan Stanley Children's Hospital

9:45 AM – 11:45 AM MST

W09--Boyz to Men in CF

Location: 106 A-C (West)

Chair: – Children's Mercy Kansas City

Chair: – Phoenix Children's

NRSCLIN

9:45 AM – 11:45 AM MST

W09.1- Assessing the rates of hypogonadism in adult males with cystic fibrosis

Location: 106 A-C (West)

Speaker: – Emory University

9:45 AM – 11:45 AM MST

W09.2- Testicular cancer

Location: 106 A-C (West)

Speaker: – Children's Mercy Kansas City

9:45 AM – 11:45 AM MST

W09.3- Sexual and Reproductive Health Knowledge, Experiences, Care Utilization, and Preferences of Adolescent and Adult Males with Cystic Fibrosis

Location: 106 A-C (West)

Speaker: – Children's Hospital of Pittsburgh

9:45 AM – 11:45 AM MST

W09.4- “SHARING” Sexual and Reproductive Health Priorities of Adults with Cystic Fibrosis and Caregivers

Location: 106 A-C (West)

Speaker: – University of Pittsburgh

9:45 AM – 11:45 AM MST

W09.5- Development of a fertility preservation telehealth counseling intervention for males with cystic fibrosis: Patient and provider perspectives

Location: 106 A-C (West)

Speaker: – University of Alabama at Birmingham School of Nursing

9:45 AM – 11:45 AM MST

W10--Airway Physiology Directed Therapies

Location: 105 AB (West)

Chair: – University of British Columbia

Chair: – University of North Carolina at Chapel Hill

APPTT

9:45 AM – 11:45 AM MST

W10.1- Pharmacodynamic effects of brensocatib in patients with cystic fibrosis

Location: 105 AB (West)

Speaker: – Vanderbilt University School of Medicine

9:45 AM – 11:45 AM MST

W10.2- Low levels of nitric oxide generated from a portable nitric oxide generator reduces biofilm bacterial load and improves mucociliary clearance

Location: 105 AB (West)

Speaker: – Temple University

9:45 AM – 11:45 AM MST

W10.3- Secretion and alkalization of airway surface liquid from CF bronchial epithelia by artificial anion transporters

Location: 105 AB (West)

Speaker: – School of Physiology, Pharmacology and Neuroscience, University of Bristol

9:45 AM – 11:45 AM MST

W10.4- The effect of discontinuing hypertonic saline or dornase alfa on mucociliary clearance in elexacaftor/tezacaftor/ivacaftor treated people with cystic fibrosis: The SIMPLIFY-MCC Study

Location: 105 AB (West)

Speaker: – Department of Medicine, Division of Pulmonary Diseases and Critical Care Medicine, The University of North Carolina at Chapel Hill, Chapel Hill, NC, USA

9:45 AM – 11:45 AM MST

W10.5- Mucus clearance therapy by an innovative synergistic approach: Early Phase I study results

Location: 105 AB (West)

Speaker: – Stanford University

9:45 AM – 11:45 AM MST

W11--Psychosocial Research Showcase

Location: 102 AB (West)

Chair: – University of Florida

Chair: – Children's Hospital of Michigan

SW/PSYCH

9:45 AM – 11:45 AM MST

W11.1- Development and pilot test of a palliative care interview guide for children with cystic fibrosis: The ADAPT-CF

Location: 102 AB (West)

Speaker: – Emory University

9:45 AM – 11:45 AM MST

W11.2- Development and implementation of a standardized process for anxiety and depression screening for youth with CF 8-11 years old

Location: 102 AB (West)

Speaker: – CCHMC Division of Social Services

9:45 AM – 11:45 AM MST

W11.3- Outcomes of a randomized controlled trial of CF-CBT in adults with cystic fibrosis with mild depression and anxiety

Location: 102 AB (West)

Speaker: – Massachusetts General Hospital

9:45 AM – 11:45 AM MST

W11.4- Validation of the CF Stress Questionnaire: A multisite study

Location: 102 AB (West)

Speaker: – Boston Children's Hospital Pulmonary

9:45 AM – 11:45 AM MST

W11.5- ACT with Cystic Fibrosis: A Multi-Site, Telehealth-Delivered Randomized Controlled Trial of Acceptance and Commitment Therapy vs Supportive Psychotherapy for Adults with Cystic Fibrosis

Location: 102 AB (West)

Speaker: – Thomas Jefferson University Hospital

9:45 AM – 11:45 AM MST

W12--Best Abstracts in GI

Location: 301 C (West)

Chair: – Hadassah Medical Center, Jerusalem

Chair: – Pediatric Gastroenterology, Seattle Children's Hospital, Seattle, WA, USA

CLIN

9:45 AM – 11:45 AM MST

W12.1- Cftr expression in GI epithelium affects amount-type of mucin secreted, smooth muscle thickness and crypt depth along its entire length

Location: 301 C (West)

Speaker: – Case Western Reserve University

9:45 AM – 11:45 AM MST

W12.2- The relationship of metabolomic profiles to clinical outcomes following CFTR rescue

Location: 301 C (West)

Speaker: – National Jewish Health

9:45 AM – 11:45 AM MST

W12.3- Mucosal inflammation of the colon and terminal ileum in people with cystic fibrosis is mild and not associated with abdominal pain or presence of polyps

Location: 301 C (West)

Speaker: – The Hospital for Sick Children, Toronto

9:45 AM – 11:45 AM MST

W12.4- Conversion of exocrine pancreatic insufficiency in pediatric patients on CFTR modulator therapy: One CF center’s experience.

Location: 301 C (West)

Speaker: – BC Children's Hospital, Vancouver, BC, Canada

9:45 AM – 11:45 AM MST

W12.5- Hepatic and Nutritional Outcomes of Hispanic and Non-Hispanic Children with Cystic Fibrosis

Location: 301 C (West)

Speaker: – Children's Hospital Colorado

9:45 AM – 11:45 AM MST

W13--Epidemiology & Detection of Infection

Location: 213 B (West)

Chair: – National Jewish Health

Chair: – The Hospital for Sick Children

IMI

9:45 AM – 11:45 AM MST

W13.1- Evolution of bacterial lung colonization status after one year of treatment with elexacaftor/tezacaftor/ivacaftor (ETI) in 198 french adult people with cystic fibrosis

Location: 213 B (West)

Speaker: – Hospices Civiles de Lyon

9:45 AM – 11:45 AM MST

W13.2- Utility of bacterial swab cultures in adults with Cystic Fibrosis

Location: 213 B (West)

Speaker: – University of Vermont

9:45 AM – 11:45 AM MST

W13.3- Home collected sputum samples for Aspergillus fumigatus detection in adults with cystic fibrosis

Location: 213 B (West)

Speaker: – University of Pennsylvania Perelman School of Medicine

9:45 AM – 11:45 AM MST

W13.4- Detection of Pseudomonas aeruginosa infection using antibodies against lipopolysaccharide and exotoxin A

Location: 213 B (West)

Speaker: – 2nd Faculty of Medicine Charles University and Motol University Hospital

9:45 AM – 11:45 AM MST

W13.5- Volatile organic compounds (VOCs) distinguish between M. avium and M. abscessus in CF sputum samples

Location: 213 B (West)

Speaker: – University of British Columbia

9:45 AM – 11:45 AM MST

W14--Lung Health in a Changing World

Location: 301 A (West)

Chair: – McMaster University

Chair: – University of Washington / Seattle Children's Research Institute

CLIN

9:45 AM – 11:45 AM MST

W14.1- The impact of COVID-19 on lung function and nutritional status in cystic fibrosis: A global observational study

Location: 301 A (West)

Speaker: – University of Toronto

9:45 AM – 11:45 AM MST

W14.2- A Multi-center Retrospective Analysis of the Clinical Efficacy of Elexacaftor-Tezacaftor-Ivacaftor in People with Cystic Fibrosis & Advanced Lung Disease: A Follow-up Study After 2 Years of Treatment

Location: 301 A (West)

Speaker: – UT Soutwhestern

9:45 AM – 11:45 AM MST

W14.3- Lung clearance index decreases in patients who do not achieve a clinically meaningful improvement in forced expiratory volume in one second following elexacaftor/tezacaftor/ivacaftor therapy

Location: 301 A (West)

Speaker: – IRCCS Cà Granda Policlinico di Milano

9:45 AM – 11:45 AM MST

W14.4- Randomized double-blind, placebo-controlled trial of oral prednisone as adjunctive treatment in pulmonary exacerbations in cystic fibrosis (PIPE Study)

Location: 301 A (West)

Speaker: – The Hospital for Sick Children (SickKids)

9:45 AM – 11:45 AM MST

W14.5- Is home spirometry accurate? Comparison of home to office spirometry in the PROMISE study

Location: 301 A (West)

Speaker: – University of Washington / Seattle Children's Research Institute

9:45 AM – 11:45 AM MST

W15--Health Equity & Social Complexity in CF

Location: 212 A-C (West)

Chair: – University of Kansas Health System

Chair: – Boston Children's Hospital

HEAC

9:45 AM – 11:45 AM MST

W15.1- Survival inequities in the Canadian Cystic Fibrosis population

Location: 212 A-C (West)

Speaker: – Dalhousie University

9:45 AM – 11:45 AM MST

W15.2- Black and Hispanic people with cystic fibrosis (PwCF) and PwCF with high lung function are less likely to be prescribed elexacaftor/tezacaftor/ivacaftor (ETI) despite having an eligible genotype

Location: 212 A-C (West)

Speaker: – Children's Hospital of Philadelphia

9:45 AM – 11:45 AM MST

W15.3- Facilitators and barriers to increasing equity in cystic fibrosis newborn screening algorithms

Location: 212 A-C (West)

Speaker: – Friedreich's Ataxia Research Alliance

9:45 AM – 11:45 AM MST

W15.4- Achieving equitable access to CFTR modulators: every patient in every country

Location: 212 A-C (West)

Speaker: – Imperial College London

9:45 AM – 11:45 AM MST

W15.5- Gender differences in mental well-being among children and adults with cystic fibrosis taking elexacaftor/tezacaftor/ivacaftor

Location: 212 A-C (West)

Speaker: – Massachusetts General Hospital/Harvard Medical School

11:30 AM – 1:45 PM MST

Affiliate Program Directors' Meeting and Core Center & Affiliate Program Meeting

Location: Sheraton Hotel- Estrella, Ahwatukee

Affiliate Meeting

11:30 AM – 2:00 PM MST

Lunch

11:30 AM – 2:00 PM MST

DIGEST Faculty & Trainee Luncheon

Location: Sheraton Hotel- North Mountain

Affiliate Meeting

12:00 PM – 12:40 PM MST

FSC01--Conversation with Monica Ulles - Joy in Work

Location: Fireside Chat A (Exhibit & Poster Hall)

Speaker: – Boston Children's Hospital

Facilitator: – Anton Yelchin CF Center Keck Medicine of USC

NRS

12:00 PM – 12:40 PM MST

FSC02--Conversation with John LiPuma

Location: Fireside Chat B (Exhibit & Poster Hall)

Speaker: – University of Michigan

Facilitator:

IMI

12:00 PM – 12:40 PM MST

RFPT03--Inflammation & Anti-Inflammatory Therapies

Location: Theater A (Exhibit & Poster Hall)

Chair: – Department of Pediatrics, Emory University

APPTT

12:00 PM – 12:40 PM MST

RFPT03.1- GATA-3 reprograms the CFTR locus to abate Th2 effector function in CD4+ T cells

Location: Theater A (Exhibit & Poster Hall)

Speaker: – Vanderbilt University Medical Center

12:00 PM – 12:40 PM MST

RFPT03.2- Sex-Specific Transcriptome Differences in Airway Neutrophils Before and After CFTR Modulator Therapy

Location: Theater A (Exhibit & Poster Hall)

Speaker: – Yale University School of Medicine

12:00 PM – 12:40 PM MST

RFPT03.3- Investigating the role of Bromodomain containing 8 (BRD8) isoforms in the innate immune response of human airway epithelial cells

Location: Theater A (Exhibit & Poster Hall)

Speaker: – Yale University

12:00 PM – 12:40 PM MST

RFPT03.4- Single cell-level pro-resolving actions of Resolvin D1 and D2 on S. aureus lung infection and inflammation in cystic fibrosis

Location: Theater A (Exhibit & Poster Hall)

Speaker: – G. d'Annunzio University of Chieti - Pescara

12:00 PM – 12:40 PM MST

RFPT03.5- Omega-6 pathway switch associates with increased neutrophil influx and structural damage, and represents a distinct disease stage independent of age, in early cf lung disease

Location: Theater A (Exhibit & Poster Hall)

Speaker: – Erasmus MC - Sophia Children's Hospital

12:00 PM – 12:40 PM MST

RFPT03.6- Tobramycin-induced secretion of P. aeruginosa 5′ tRNA-fMet halves in outer membrane vesicles suppresses lung inflammation via AGO2-mediated gene silencing

Location: Theater A (Exhibit & Poster Hall)

Speaker: – University of Colorado Anschutz Medical Campus

12:00 PM – 12:40 PM MST

RFPT03.7- Role of IL-1β in innate host defense of normal airway epithelia

Location: Theater A (Exhibit & Poster Hall)

Speaker: – University of North Carolina at Chapel Hill

12:00 PM – 12:40 PM MST

RFPT03.8- Low-density neutrophils in adult CF are associated with lung disease progression and display distinct antimicrobial capacity

Location: Theater A (Exhibit & Poster Hall)

Speaker: – CHU de Québec Research Center, Laval University

12:00 PM – 12:40 PM MST

RFPT04--QI Abstracts

Location: Theater B (Exhibit & Poster Hall)

Chair: – Department of Pediatrics, Medical College of Wisconsin, Children's Wisconsin

Chair: – University of Washington / Seattle Children's Hospital

CLIN

12:00 PM – 12:40 PM MST

RFPT04.1- Sexual and Reproductive Health Knowledge in Cystic Fibrosis Patients: An Evaluation and An Intervention.

Location: Theater B (Exhibit & Poster Hall)

Speaker: – University of Miami

12:00 PM – 12:40 PM MST

RFPT04.2- Identify yourself- self-reported demographics and SDOH

Location: Theater B (Exhibit & Poster Hall)

Speaker: – UVA Children's

12:00 PM – 12:40 PM MST

RFPT04.3- Improving the Quantity not Sufficient Rates in Sweat Tests

Location: Theater B (Exhibit & Poster Hall)

Speaker: – UTSW/Children's Health

12:00 PM – 12:40 PM MST

RFPT04.4- Food insecurity screening: A 2-year CF clinic QI initiative

Location: Theater B (Exhibit & Poster Hall)

Speaker: – Primary Children's Hospital

12:00 PM – 12:40 PM MST

RFPT04.5- Increasing timely completion of baseline safety assessments prior to initiating modulator therapy

Location: Theater B (Exhibit & Poster Hall)

Speaker: – Oregon Health & Science University

12:00 PM – 12:40 PM MST

RFPT04.6- Improving Care for CF Adults with Advanced Lung Disease

Location: Theater B (Exhibit & Poster Hall)

Speaker: – University of North Carolina at Chapel Hill

12:00 PM – 12:40 PM MST

RFPT04.7- Improving Face-to-Face Cystic Fibrosis Clinic Flow Post Pandemic

Location: Theater B (Exhibit & Poster Hall)

Speaker: – Dell Children's Medical Center of Central Texas

12:00 PM – 12:40 PM MST

RFPT04.8- Improving CF clinic efficiency: A QI project arising from patient experience data

Location: Theater B (Exhibit & Poster Hall)

Speaker: – Children's Healthcare of Atlanta

12:00 PM – 1:30 PM MST

Junior Investigator Poster Judging Time

Location: Exhibit & Poster Hall

Chair: – National Jewish Health

Chair: – Emory University School of Medicine

Chair: – Massachusetts General Hospital/Harvard Medical School

Chair: – Indiana University School of Medicine

Panelist: – Behavioral Health Systems Research, Miami, FL, USA

Panelist: – University of Pennsylvania

Panelist: – University of Texas Southwestern Medical Center

Panelist: – University of Washington

Panelist:

Panelist: – Yale University School of Medicine

Panelist: – CWRU

Panelist:

Panelist: – Emory University School of Medicine

Panelist: – University of North Carolina

Panelist:

Poster Presenter: – University of Oklahoma School of Community Medicine

Poster Presenter: – Imperial College London

Poster Presenter: – University Of Wisconsin School Of Medicine & Public Health

Poster Presenter:

Poster Presenter: – Children's Hospital Colorado

Poster Presenter: – Emory University

Poster Presenter: – University of Toronto

Poster Presenter: – University Hospital Heidelberg

Poster Presenter: – National Heart and Lung Institute, Imperial College London, London, UK; Royal Brompton and Harefield, Guy's and St Thomas' NHS Foundation Trust, London, UK

Poster Presenter: – Johns Hopkins School of Medicine

Poster Presenter: – Yale School of medicine

Poster Presenter: – Cedars Sinai Medical Center

Poster Presenter: – The University of Iowa

Poster Presenter: – University College Cork

Poster Presenter: – University of Rochester Medical Center

Poster Presenter: – Charité - Universitätsmedizin Berlin

Poster Presenter: – University of British Columbia

Poster Presenter: – Dartmouth College

Poster Presenter: – University of Washington

Poster Presenter: – Dalhousie University

12:00 PM – 1:30 PM MST

SGS--Special Grants Session

Location: 126 A-C (North)

12:00 PM – 1:30 PM MST

PACE Program Luncheon

Location: Sheraton Hotel- Laveen

Affiliate Meeting

12:00 PM – 1:30 PM MST

Resident Roundtable

Location: Sheraton Hotel- Maryvale

Affiliate Meeting

12:00 PM – 1:30 PM MST

LL01--Making Psychosocial Research Accessible

Location: 131 AB (North)

Chair: – West Virginia University

Chair: – Cedar Crest College

Speaker: – University of Florida

Speaker: – Cincinnati Children's Hospital Medical Center, Divisions of Behavioral Medicine and Clinical Psychology & Pulmonary Medicine

Speaker: – Massachusetts General Hospital

Speaker: – Hartford Healthcare, Hartford, CT, USA

Speaker: – University of Colorado SOM/Children's Hospital Colorado

Speaker: – CF Foundation

Speaker: – Johns Hopkins University

Speaker: – Children's Hospital of Pittsburgh

SW/PSYCH

12:00 PM – 1:30 PM MST

LL02--Cellular Barriers to Nucleotide-Based (PTAC-Type) Interventions

Location: 228 AB (North)

Chair: – Cystic Fibrosis Foundation

Chair: – University College Cork

Speaker: – Cystic Fibrosis Foundation

Speaker: – University College Cork

PTAC/CFTR

12:00 PM – 1:30 PM MST

LL03--Advanced Liver Disease

Location: 129 AB (North)

Chair: – Oklahoma University Health Sciences Center

Chair: – Baylor College of Medicine/Texas Children's Hospital

Speaker: – Oklahoma University Health Sciences Center

CLIN

12:00 PM – 1:30 PM MST

LL04--Self-Care in a High Stress Environment

Location: 226 A-C (North)

Chair: – Dartmouth Health

Chair: – Children's Healthcare of Atlanta

Speaker: – Cystic Fibrosis Research Institute

Speaker: – Stanford Medicine children's Health

Speaker: – Mission Children's Specialists

PT/RTSW/PSYCH

12:00 PM – 1:30 PM MST

LL05--In the Beginning, There was Nutrition: Early Childhood Feeding

Location: 127 A-C (North)

Chair: – University of Michigan

Chair: – St. Louis Children's Hospital

Community Speaker: – Community Member

Speaker: – University of Michigan

Speaker: – St. Louis Children's Hospital

Speaker: – Nationwide Children's Hospital

Speaker: – University of Michigan

Speaker: – Riley Hospital for Children

NTRSW/PSYCH

12:00 PM – 1:30 PM MST

LL06--Risky Business: Psychosocial Interventions for High Risk Behaviors

Location: 125 AB (North)

Chair: – St. Michael's Hospital, Unity Health Toronto

Chair: – Children's Health Dallas

Speaker: – Nationwide Children's Hospital

Speaker: – UNC- Chapel Hill

Speaker: – Cook Children's Medical Center

Speaker: – Children's Health Dallas

SW/PSYCH

12:00 PM – 1:30 PM MST

LL07--Management of NTM Infections

Location: 225 AB (North)

Chair: – University of Colorado and Children's Hospital Colorado

Chair: – Copenhagen CF Center

Speaker: – University of Colorado and Children's Hospital Colorado

Speaker: – Copenhagen CF Center

Speaker: – National Jewish Health

IMI

12:00 PM – 1:30 PM MST

RT01- Brainstorming about biomarkers: Where do we go now?

Location: 224 AB (North)

Facilitator: – National Jewish Health

CLIN

12:00 PM – 1:30 PM MST

RT02- Do we have an infection control problem? Identifying and investigating possible outbreaks in your clinic and hospital

Location: 224 AB (North)

Facilitator: – National Jewish Health

CLIN

12:00 PM – 1:30 PM MST

RT03- The Patient Navigator: the solution to every problem in the CF clinic!

Location: 224 AB (North)

Facilitator: – National Jewish Health

CLIN

12:00 PM – 1:30 PM MST

RT04- Growing Your Career Into Management

Location: 224 AB (North)

Facilitator: – UT Southwestern Medical Center

CLIN

12:00 PM – 1:30 PM MST

RT05- CF Exacerbation Symptoms

Location: 224 AB (North)

Facilitator: – University of Washington

CLIN

12:00 PM – 1:30 PM MST

RT06- Timing of Lung Transplant Referral

Location: 224 AB (North)

Facilitator: – Hospital University of Pennsylvania

CLIN

12:00 PM – 1:30 PM MST

RT07- How to manage staff turnover during the “Great Resignation”

Location: 224 AB (North)

Facilitator: – national jewish health

CLIN

12:00 PM – 1:30 PM MST

RT08- Its that time again- how to make the most of your Program Site Visit

Location: 224 AB (North)

Facilitator: – Helen DeVos Children's Hospital at Corewell Health (formerly Spectrum Health

CLIN

12:00 PM – 1:30 PM MST

RT09- Motility basics in CF

Location: 224 AB (North)

Facilitator: – Saint Louis University School of Medicine

CLIN

12:00 PM – 1:30 PM MST

RT10- Gut-Lung Axis & Diet

Location: 224 AB (North)

Facilitator: – Pediatric Gastroenterology, Seattle Children's Hospital, Seattle, WA, USA

CLIN

12:00 PM – 1:30 PM MST

RT11- Small Bowel Disorders

Location: 224 AB (North)

Facilitator:

CLIN

12:00 PM – 1:30 PM MST

RT12- A Review of Newborn Screening Guidelines

Location: 224 AB (North)

Facilitator: – Boston Children's Hospital

NRS

12:00 PM – 1:30 PM MST

RT13- The Transition Toolbox for a Smooth Transition

Location: 224 AB (North)

Facilitator: – Froedtert Hospital

NRS

12:00 PM – 1:30 PM MST

RT14- Get Started: How to Quality Improve

Location: 224 AB (North)

Facilitator: – Prisma Health Children's Hospital-Upstate

NRS

12:00 PM – 1:30 PM MST

RT15- Optimizing Multidisciplinary Care: The Vital Roles of Pharmacists and Pharmacy Technicians

Location: 224 AB (North)

Facilitator: – University of Kentucky

PHARM

12:00 PM – 1:30 PM MST

RT16- The Evolving Roles of CF Pharmacy Technicians

Location: 224 AB (North)

Facilitator: – T. C. Thompson’s Children’s Hospital at Erlanger

PHARM

12:00 PM – 1:30 PM MST

RT17- “Optimizing Your Gut”- Medication Management of SIBO and other GI

Location: 224 AB (North)

Facilitator: – Children's Hospital & Medical Center Cystic Fibrosis Care Center

PHARM

12:00 PM – 1:30 PM MST

RT18- Adult Nutrition

Location: 229 AB (North)

Facilitator: – Baylor College of Medicine

NTR

12:00 PM – 1:30 PM MST

RT19- Nutrition Focused Physical Exam (NFPE)

Location: 229 AB (North)

Facilitator: – University of Vermont Medical Center

NTR

12:00 PM – 1:30 PM MST

RT20- Pregnancy

Location: 229 AB (North)

Facilitator: – MaineHealth

NTR

12:00 PM – 1:30 PM MST

RT21- "I only have 10 minutes!" Prioritizing PT Interventions/Assessments During Clinic

Location: 229 AB (North)

Facilitator: – The Johns Hopkins Hospital

PT/RT

12:00 PM – 1:30 PM MST

RT22- Exercise Field Tests for Clinic "And Beyond!

Location: 229 AB (North)

Facilitator: – JW Ruby Memorial Hospital, WVU Medicine

PT/RT

12:00 PM – 1:30 PM MST

RT23- Exercising with Oxygen: Safe exercise prescription and progression for people with stable but lower lung function

Location: 229 AB (North)

Facilitator: – University Hospitals Cleveland Medical Center

PT/RT

12:00 PM – 1:30 PM MST

RT24- Individualized RT Care Plans

Location: 229 AB (North)

Facilitator: – Riley Hospital for Children at IU Health

PT/RT

12:00 PM – 1:30 PM MST

RT25- New RT/PT to the CF Clinic

Location: 229 AB (North)

Facilitator: – St. Luke's

PT/RT

12:00 PM – 1:30 PM MST

RT26- Sustaining PT in the CF Care Center

Location: 229 AB (North)

Facilitator: – Dell Children's Medical Center of Central Texas

PT/RT

12:00 PM – 1:30 PM MST

RT27- Transition to Adult/Independent Care

Location: 229 AB (North)

Facilitator: – UH Rainbow Babies and Children's Hospital

PT/RT

12:00 PM – 1:30 PM MST

RT28- Environmental Factors that Influence CFTR Biogenesis, Expression, and Activity

Location: 229 AB (North)

Facilitator: – The Ohio State University

PTAC/CFTRAPPTTIMI

12:00 PM – 1:30 PM MST

RT29- Proteomic-driven advances in studies of CF

Location: 229 AB (North)

Facilitator: – Vanderbilt University

PTAC/CFTRAPPTT

12:00 PM – 1:30 PM MST

RT30- Emerging viral and non-viral delivery vehicles for genetic rescue of airway epithelium

Location: 229 AB (North)

Facilitator: – The University of Texas at Austin

PTAC/CFTR

12:00 PM – 1:30 PM MST

RT31- Techniques to detect CFTR function in cells and tissues

Location: 229 AB (North)

Facilitator: – University of Alabama at Birmingham

PTAC/CFTR

12:00 PM – 1:30 PM MST

RT32- Child Life

Location: 229 AB (North)

Facilitator: – Mayo Clinic

SW/PSYCH

12:00 PM – 1:30 PM MST

RT33- Social Determinants of Health Screenings

Location: 229 AB (North)

Facilitator: – Boston Children's Hospital/Brigham and Women's Hospital

SW/PSYCH

12:00 PM – 1:30 PM MST

RT34- Resources for the Spanish-Speaking Community

Location: 229 AB (North)

Facilitator: – UCSF Benioff Children's Hospital

Community Speaker:

SW/PSYCH

12:00 PM – 1:30 PM MST

TPS02--Bacteriophage and Emerging Therapies

Location: Theater C (Exhibit & Poster Hall)

Chair: – Yale University

Chair: – University of Pittsburgh

IMI

12:00 PM – 1:30 PM MST

TPS02.1- Bacteriophages that Kill Pseudomonas aeruginosa Induce Heterogenous Cellular Responses in the Airway Epithelium

Location: Theater C (Exhibit & Poster Hall)

Speaker:

12:00 PM – 1:30 PM MST

TPS02.2- Targeting eukaryotic-like serine/threonine protein kinases in Staphylococcus aureus to combat antimicrobial resistance in CF clinical isolates

Location: Theater C (Exhibit & Poster Hall)

Speaker: – The Ohio State University

12:00 PM – 1:30 PM MST

TPS02.3- Bacteriophages, antibiotics, and small-molecule adjuvants against antibiotic resistant Stenotrophomonas maltophilia

Location: Theater C (Exhibit & Poster Hall)

Speaker: – UC Irvine

12:00 PM – 1:30 PM MST

TPS02.4- Recombinant Pyocins as Emerging Therapies against Respiratory Infections with Pseudomonas aeruginosa

Location: Theater C (Exhibit & Poster Hall)

Speaker: – Emory University

12:00 PM – 1:30 PM MST

TPS02.5- Evaluating iron induced Aspergillus proteases: a central effector for Th-2 immune response pathway in allergic bronchopulmonary aspergillosis in patients with cystic fibrosis

Location: Theater C (Exhibit & Poster Hall)

Speaker: – Stanford University

12:00 PM – 1:30 PM MST

TPS02.6- Bacteriophage Therapy for Pseudomonas aeruginosa Infections in People with Cystic Fibrosis

Location: Theater C (Exhibit & Poster Hall)

Speaker: – University of Pittsburgh

12:00 PM – 1:30 PM MST

TPS02.7- A nanoparticle lipid droplet formulation of the silver salt of ibuprofen to treat infections with multidrug-resistant Pseudomonas aeruginosa

Location: Theater C (Exhibit & Poster Hall)

Speaker: – Texas A&M School of Medicine

12:00 PM – 1:30 PM MST

TPS02.8- Efficacy of the lysin exebacase in addition to vancomycin in a rabbit lung infection model caused by a cystic fibrosis methicillin resistant Staphylococcus aureus (CF-MRSA) clinical isolate

Location: Theater C (Exhibit & Poster Hall)

Speaker: – ContraFect Corporation

12:00 PM – 1:30 PM MST

TPS02.9- Mycobacterium trehalose polyphleates are required for infection of clinically useful mycobacteriophages

Location: Theater C (Exhibit & Poster Hall)

Speaker: – University of Pittsburgh

12:00 PM – 1:30 PM MST

TPS02.10- ELD607, a Novel Orai1 Antagonist, Reduces Inflammation and Clears Burkholderia cepacia Complexand Multidrug-Resistant Pseudomonas aeruginosa from the Lungs.

Location: Theater C (Exhibit & Poster Hall)

Speaker: – Eldec Pharmaceuticals

12:50 PM – 1:30 PM MST

ABC’s of Personal Safety: Essential Concepts for Self Defense

Location: Theater B (Exhibit & Poster Hall)

Wellness Activity

12:50 PM – 1:30 PM MST

FSC03--Conversation with Chris Goss

Location: Fireside Chat A (Exhibit & Poster Hall)

Speaker: – University of Washington

Facilitator: – St. Michael's Hospital, Unity Health Toronto

CLIN

12:50 PM – 1:30 PM MST

FSC04--Conversation with David Young

Location: Fireside Chat B (Exhibit & Poster Hall)

Speaker: – University of Utah College of Pharmacy

Facilitator: – Cystic Fibrosis Foundation

PHARM

12:50 PM – 1:30 PM MST

RFPT05--Access, Care Delivery, & Cost

Location: Theater A (Exhibit & Poster Hall)

Chair: – University of California, San Francisco

Chair: – Cystic Fibrosis Foundation

HEAC

12:50 PM – 1:30 PM MST

RFPT05.1- Primary Care Utilization in Cystic Fibrosis: A Comparative Analysis of Patient and Provider Perceptions

Location: Theater A (Exhibit & Poster Hall)

Speaker: – Stanford University

12:50 PM – 1:30 PM MST

RFPT05.2- Addressing access barriers to CF-related diabetes care

Location: Theater A (Exhibit & Poster Hall)

Speaker: – Cystic Fibrosis Foundation

12:50 PM – 1:30 PM MST

RFPT05.3- Effective approach to improve CF care delivery in resource-challenged regions

Location: Theater A (Exhibit & Poster Hall)

Speaker: – Children's of Alabama

12:50 PM – 1:30 PM MST

RFPT05.4- What is the financial burden of out-of-pocket expenses in the Canadian cystic fibrosis population?

Location: Theater A (Exhibit & Poster Hall)

Speaker: – Dalhousie University

12:50 PM – 1:30 PM MST

RFPT05.5- Newborn screening: The great equalizer in diagnosing non-white Canadians with CF?

Location: Theater A (Exhibit & Poster Hall)

Speaker: – Cystic Fibrosis Canada

12:50 PM – 1:30 PM MST

RFPT05.6- The lived experiences of African American individuals with cystic fibrosis

Location: Theater A (Exhibit & Poster Hall)

Speaker: – University of Alabama at Birmingham School of Nursing

12:50 PM – 1:30 PM MST

RFPT05.7- Food insecurity screening in people living with cystic fibrosis

Location: Theater A (Exhibit & Poster Hall)

Speaker: – MaineHealth

12:50 PM – 1:30 PM MST

RFPT05.8- Pushing beyond the binary: A call to action for inclusive data collection for persons living with cystic fibrosis

Location: Theater A (Exhibit & Poster Hall)

Speaker: – Boston Children's Hospital, Brigham and Women's Hospital

1:30 PM – 2:00 PM MST

30 Minute Guided Meditation

Location: 230 North

2:00 PM – 3:30 PM MST

TPS03--Pharmacotherapy Thematic Poster Session.

Location: Theater C (Exhibit & Poster Hall)

Chair: – BC Children's Hospital, Vancouver, BC, Canada

Chair: – University of Kansas Health System

PHARM

2:00 PM – 3:30 PM MST

TPS03.1- The evolution of pharmacy services at US CFF-accredited centers: ten years later

Location: Theater C (Exhibit & Poster Hall)

Speaker: – University of Kentucky

2:00 PM – 3:30 PM MST

TPS03.2- Documentation Practices of Cystic Fibrosis (CF) Pharmacists: An Opportunity for Discipline-Wide Quality Improvement

Location: Theater C (Exhibit & Poster Hall)

Speaker: – University of Michigan / Michigan Medicine

2:00 PM – 3:30 PM MST

TPS03.3- Contemporary analysis in pancreatic enzyme use in the Nova Scotian Cystic Fibrosis population

Location: Theater C (Exhibit & Poster Hall)

Speaker: – Dalhousie University

2:00 PM – 3:30 PM MST

TPS03.4- Selective serotonin reuptake inhibitor response in persons with cystic fibrosis

Location: Theater C (Exhibit & Poster Hall)

Speaker: – Indiana Unversity

2:00 PM – 3:30 PM MST

TPS03.5- Outcomes Of Patients With Intermittent Versus Continuous Access To CFTR Modulator Therapy in Turkey

Location: Theater C (Exhibit & Poster Hall)

Speaker: – Marmara University Medical Faculty

2:00 PM – 3:30 PM MST

TPS03.6- Pharmacokinetic variability of CFTR modulators from standard and alternative regimens

Location: Theater C (Exhibit & Poster Hall)

Speaker: – University of Alabama at Birmingham

2:00 PM – 3:30 PM MST

TPS03.7- Elexacaftor-Tezacaftor-Ivacaftor associated rash management at a large pediatric cystic fibrosis center: a multidisciplinary approach

Location: Theater C (Exhibit & Poster Hall)

Speaker: – Texas Children's Hospital

2:00 PM – 3:30 PM MST

TPS03.8- Evaluation of the adverse effects of elexacaftor/tezacaftor/ivacaftor in pediatric cystic fibrosis patients age 6-11 years

Location: Theater C (Exhibit & Poster Hall)

Speaker: – Riley Hospital for Children at IU Health

2:00 PM – 3:30 PM MST

TPS03.9- Analysis of cholesterol levels after initiation of elexacaftor/tezacaftor/ivacaftor

Location: Theater C (Exhibit & Poster Hall)

Speaker: – University of Virginia (UVA) Health

2:00 PM – 3:30 PM MST

TPS03.10- Alopecia in children and adults with cystic fibrosis on elexacaftor/tezacaftor/ivacaftor

Location: Theater C (Exhibit & Poster Hall)

Speaker: – University of North Carolina Health

2:00 PM – 4:00 PM MST

S01--Novel Approaches to Treating Pulmonary Infections

Location: 103 AB (West)

Chair: – University of Pittsburgh

Chair: – Children's Hospital Colorado, Univ. of Colorado Anschutz Med. Campus

IMI

2:00 PM – 4:00 PM MST

S01.1- New approaches to target antibiotic-resistant bacteria in CF

Location: 103 AB (West)

Speaker: – Cedars-Sinai Medical Center

2:00 PM – 4:00 PM MST

S01.2- Phage therapy for the treatment of antibiotic-resistant bacterial infections

Location: 103 AB (West)

Speaker: – University of Pittsburgh

2:00 PM – 4:00 PM MST

S01.3- Machine learning and chemogenomics to identify new antimicrobials and their mode of action in Burkholderia cenocepacia

Location: 103 AB (West)

Speaker: – University of Manitoba

2:00 PM – 4:00 PM MST

S01.4- Emerging new approaches to improve treatment of Pseudomonas aeruginosa infections.

Location: 103 AB (West)

Speaker: – McGill University

2:00 PM – 4:00 PM MST

S02--Year's in Review

Location: 207 Lecture Hall (West)

Chair: – University of Michigan

Chair: – University at Buffalo/UBMD Pediatrics

CLIN

2:00 PM – 4:00 PM MST

S02.1- CFTR Modulators in Children: Nearing Primary Prevention

Location: 207 Lecture Hall (West)

Speaker: – Department of Pediatrics

2:00 PM – 4:00 PM MST

S02.2- A compilation, explanation, and presentation on pulmonary exacerbation: An update

Location: 207 Lecture Hall (West)

Speaker: – Seattle Children's Hospital/University of Washington

2:00 PM – 4:00 PM MST

S02.3- Advances in diagnosis and management of GI manifestations of CF

Location: 207 Lecture Hall (West)

Speaker: – Hospital for Sick Children

2:00 PM – 4:00 PM MST

S02.4- Progress in diagnosis and management of CF-related diabetes

Location: 207 Lecture Hall (West)

Speaker: – St. Michael's Hospital

2:00 PM – 4:00 PM MST

S03--Pro Con - Care Model Compliant

Location: 301 D (West)

Chair: – Halite Solutions Group

Chair: – Medical University of SC

NRS

2:00 PM – 4:00 PM MST

S03.1- Setting the Stage: Where We Were, Where We Are & Where We Are Going

Location: 301 D (West)

Speaker: – Monroe Carell Jr. Children's Hospital at Vanderbilt

2:00 PM – 4:00 PM MST

S03.2 - Changes in Registry Data: What’s Happening at the National Level

Location: 301 D (West)

Speaker: – Cystic Fibrosis Foundation

2:00 PM – 4:00 PM MST

S03.3- Care Model

Location: 301 D (West)

Community Speaker:

Community Speaker: – Person with CF

Community Speaker: – VCU ADULT CF CENTER

2:00 PM – 4:00 PM MST

S03.4- Emotional Wellness

Location: 301 D (West)

Community Speaker:

Community Speaker: – Person with CF

Community Speaker: – VCU ADULT CF CENTER

2:00 PM – 4:00 PM MST

S04--How Much is Too Much? Taking on the Challenges of Costs of CF Care

Location: 105 AB (West)

Chair: – Boston Children’s Hospital/Brigham & Women’s Hospital

Chair: – URMC Pediatric Pulmonary

HEAC

2:00 PM – 4:00 PM MST

S04.1- The Business Case for CF Care

Location: 105 AB (West)

Speaker: – Department of Pediatrics, Johns Hopkins University, Baltimore, MD

2:00 PM – 4:00 PM MST

S04.2- Value Based CF Care

Location: 105 AB (West)

Speaker: – URMC Pediatric Pulmonary

2:00 PM – 4:00 PM MST

S04.3- Payment and Access to CF Therapies: The Impact of Pay and Third Party Programs

Location: 105 AB (West)

Speaker: – UNC Medical Center

2:00 PM – 4:00 PM MST

S04.4- A Changing Landscape to Improve the Cost of CF Care

Location: 105 AB (West)

Speaker: – Cystic Fibrosis Foundation

2:00 PM – 4:00 PM MST

S05--Emerging Topics in CF Lung Disease

Location: 301 A (West)

Chair: – University of Toronto

Chair: – Boston Children's Hospital, Brigham & Women's Hospital

CLIN

2:00 PM – 4:00 PM MST

S05.1- Role of biologics in managing asthma overlap syndromes in CF

Location: 301 A (West)

Speaker: – University of British Columbia

2:00 PM – 4:00 PM MST

S05.2- Impact of COVID-19 infection on people with CF: An international perspective

Location: 301 A (West)

Speaker: – St. Michael's Hospital, Unity Health Toronto

2:00 PM – 4:00 PM MST

S05.3- Advances in Phage Therapy as a Therapy for CF

Location: 301 A (West)

Speaker: – Yale University

2:00 PM – 4:00 PM MST

S05.4- Is LCI ready for primetime?: how to monitor lung disease in young children

Location: 301 A (West)

Speaker: – University of Toronto, Hospital for Sick Children

2:00 PM – 4:00 PM MST

S06--Trauma-Informed Care for the Healthcare Team

Location: 301 C (West)

Chair: – UNC-CH

Chair: – Cook Children's Medical Center

SW/PSYCH

2:00 PM – 4:00 PM MST

S06.1- Gender-Based Violence

Location: 301 C (West)

Speaker: – UNC

2:00 PM – 4:00 PM MST

S06.2- TBRI: Trust Based Relational Intervention

Location: 301 C (West)

Speaker: – Lehigh Valley Reilly Children's Hospital

2:00 PM – 4:00 PM MST

S06.3- Medical Trauma

Location: 301 C (West)

Speaker: – University of Kentucky

2:00 PM – 4:00 PM MST

S07--Multi-Disciplinary Approaches to CF-Related Diabetes

Location: 101 A-C (West)

Chair: – Emory University

Chair: – Johns Hopkins University

EPP

2:00 PM – 4:00 PM MST

S07.1- CFTR modulator therapy on the endocrine pancreas in the CF ferret model

Location: 101 A-C (West)

Speaker: – University of Iowa

2:00 PM – 4:00 PM MST

S07.2- Comprehensive Analysis of the Cystic Fibrosis Pancreas

Location: 101 A-C (West)

Speaker: – University of Washington and VA Puget Sound Health Care System

2:00 PM – 4:00 PM MST

S07.3- Investigating beta cell reactive T cells in cystic fibrosis-related diabetes

Location: 101 A-C (West)

Speaker: – Benaroya Research Institute

2:00 PM – 4:00 PM MST

S07.4- Current CFRD trials

Location: 101 A-C (West)

Speaker: – University of Iowa

2:00 PM – 4:00 PM MST

S08--HEMT Effects on the Hallmarks of CF Airway Disease: Why do They Work or Not?

Location: 106 A-C (West)

Chair: – Department of Pediatrics m. S. Pneumology, Immunology and Intensive Care Medicine, Charité, Universitätsmedizin, Berlin, Germany

Chair: – Washington University School of Medicine in St. Louis

Community Speaker:

APPTT

2:00 PM – 4:00 PM MST

S08.1- Restoration of epithelial CFTR function

Location: 106 A-C (West)

Speaker: – Charité- Universitätsmedizin Berlin

2:00 PM – 4:00 PM MST

S08.2- Obstruction, mucus, and mucociliary clearance

Location: 106 A-C (West)

Speaker: – The University of North Carolina at Chapel Hill

2:00 PM – 4:00 PM MST

S08.3- Inflammation and immunity

Location: 106 A-C (West)

Speaker: – RCSI University of Medicine and Health Sciences

2:00 PM – 4:00 PM MST

S08.4- Infection and airway dysbiosis

Location: 106 A-C (West)

Speaker: – University of Michigan Health

2:00 PM – 4:00 PM MST

S09--We Need to Talk About It: Menopause, Menstrual Cycles, & Puberty

Location: 231 A-C (North)

Chair: – University of Pittsburgh

Chair: – University of Pennsylvania Perelman School of Medicine

CLIN

2:00 PM – 4:00 PM MST

S09.1- Sex Disparities in CF Health and Survival

Location: 231 A-C (North)

Speaker: – University of Texas Southwestern Medical Center

2:00 PM – 4:00 PM MST

S09.2- Puberty in CF

Location: 231 A-C (North)

Speaker: – Johns Hopkins University School of Medicine

2:00 PM – 4:00 PM MST

S09.3- Impact of the menstrual cycle and use of hormonal contraception on CF health

Location: 231 A-C (North)

Speaker: – University of California San Diego

2:00 PM – 4:00 PM MST

S09.4- Menopause in CF

Location: 231 A-C (North)

Speaker: – University of Illinois at Chicago

2:00 PM – 4:00 PM MST

S10--An Update on the Changing Face of Physical and Respiratory Therapy in an Era of Highly Effective Modulator Therapies (HEMT): Part 2

Location: 212 A-C (West)

Chair: – Dell Children's Medical Center of Central Texas

Chair: – University of British Columbia

PT/RT

2:00 PM – 4:00 PM MST

S10.1- To Inhale or Not to Inhale, Part 2

Location: 212 A-C (West)

Speaker: – Johns Hopkins Hospital

2:00 PM – 4:00 PM MST

S10.2- Airway Clearance through the Ages, Looking Back, Looking Forward

Location: 212 A-C (West)

Speaker: – BC Children's Hospital

2:00 PM – 4:00 PM MST

S10.3- Reframing Exercise and Airway Clearance Post-ETI

Location: 212 A-C (West)

Speaker: – Royal Hospital for Children and Young People, Edinburgh

2:00 PM – 4:00 PM MST

S10.4- Body Composition, Exercise, and Pulmonary Function

Location: 212 A-C (West)

Speaker: – Dell Children's Medical Center of Central Texas

2:00 PM – 4:00 PM MST

S11--Nucleotide Delivery to CF Lungs: Emerging Strategies and Barriers to Success

Location: 102 AB (West)

Chair: – University of Michigan

Chair: – University of Iowa

PTAC/CFTRAPPTT

2:00 PM – 4:00 PM MST

S11.1- Immunological Considerations and Lung Gene Delivery

Location: 102 AB (West)

Speaker: – Tulane University

2:00 PM – 4:00 PM MST

S11.2- Vehicles for viral vector delivery to the airways

Location: 102 AB (West)

Speaker: – University of Iowa

2:00 PM – 4:00 PM MST

S11.3- Overcoming mucus barriers with nanomedicines

Location: 102 AB (West)

Speaker: – Johns Hopkins University School of Medicine

2:00 PM – 4:00 PM MST

S11.4- Polymeric Nanoparticle Strategies to Overcome Barriers for Systemic CF Gene Therapy

Location: 102 AB (West)

Speaker: – University of Michigan

4:30 PM – 6:00 PM MST

PL1- Genetic Therapies for All: Harnessing Cross-Disease Knowledge for Breakthroughs in Cystic Fibrosis

Location: North Ballroom A-D

Speaker: – University of Iowa

Speaker:

6:00 PM – 7:30 PM MST

Welcome Reception

Location: Exhibit & Poster Hall 300 level (West)

7:30 PM – 9:00 PM MST

Partnerships for Sustaining Daily Care

Location: Sheraton Hotel- Desert Sky

Affiliate Meeting

8:00 PM – 9:00 PM MST

Experience of Care (XoC) Survey Champions

Location: Sheraton Hotel- Deer Valley

Affiliate Meeting

8:00 PM – 9:30 PM MST

Military Affiliate Program Meeting

Location: Sheraton Hotel- Camelback

Affiliate Meeting

8:00 PM – 9:30 PM MST

DIGEST - ENVISION Reception

Location: Renaissance Hotel- Maricopa

Affiliate Meeting

8:00 PM – 9:45 PM MST

Canadian CF Newborn Screening Meeting

Location: Sheraton Hotel- Encanto AB

Affiliate Meeting